RF calibration of on-chip DfT chain by DC stimuli and statistical multivariate regression technique

Objective We aimed to compare blood pressure (BP) levels recorded using the semiautomatic oscillometric Omron i-C10 blood pressure device in patients with or without hypertension in three different settings: 1, when used by a doctor or a nurse at the office (OBP); 2, when used for self-measurement by the patient at the office (SMOBP); 3, when used for 7 consecutive days at home (HBP). Methods A total of 247 subjects were invited to participate but 78 of these declined and a further 7 were excluded, leaving a final cohort of 162 participants. Results Mean OBP was higher than HBP (difference 8.1±14/3.1±8.8 mmHg, p<0.0001) and so was SMOBP compared with HBP (difference 7.0±13/4.2±7.3 mmHg, p<0.0001). Sixteen participants (9.9%) had ≥10 mmHg higher systolic SMOBP than OBP and 28 (17%) participants had ≥10 mmHg lower systolic SMOBP than OBP. Subjects that were current smokers had a larger mean difference between systolic OBP and SMOBP than non-smokers (OBP SMOBP in smokers: 6.6 ± 9.4 mmHg, OBP SMOBP in non-smokers: 0.5 ± 9.2 mmHg, p= 0.011 between groups) Conclusion Self-measurement of BP in the office does not preclude an increase in BP when levels in the individual patients are compared with HBP using the same equipment. Thus SMOBP with a semi-automatic device does not achieve the reduction of the white-coat effect in the same manner as fully automatic devices.